Daniel S. Reich, Ph.D., M.D.

I am a resident in neurology, diagnostic radiology, and neuroradiology at Johns Hopkins Hospital.

I received my Ph.D. from The Rockefeller University and M.D. from Cornell University Medical College.

My Ph.D. advisors were Bruce Knight and Jonathan Victor (lab home page; personal home page).

Address:
600 N Wolfe St / Pathology 509
Baltimore, MD 21287
e-mail

Neurology Lectures

Neuroradiology Teaching File

Marathon Pictures

Music

Research Interests

Scientific Publications

    Thesis

• Reich, DS (2000). Information encoding by individual neurons and groups of neurons in the primary visual cortex. New York, Rockefeller University: 216 pp.

• Abstract

• Download: pdf (4.43 MB); zipped Microsoft Word 2000 (1.97 MB; includes hyperlinked figures, tables, and table of contents)

    Papers

1. Venkataramana A, Pardo CA, McArthur JC, Kerr DA, Irani DN, Griffin JW, Burger P, Reich DS, Calabresi PA, Nath A. Immune reconstitution inflammatory syndrome in the CNS of HIV-infected patients. Neurology 2006;67:383-388.

2. Smith SA, Farrell JA, Jones CK, Reich DS, Calabresi PA, van Zijl PC. Pulsed magnetization transfer imaging with body coil transmission at 3 Tesla: Feasibility and application. Magn Reson Med 2006;56:866-875.

3. Reich DS, Smith SA, Zackowski KM, Gordon-Lipkin E, Jones CK, Mori S, van Zijl PCM, Calabresi PA. Multiparametric analysis of the corticospinal tract in MS. Neuroimage 2006;submitted

4. Reich DS, Smith SA, Jones CK, Zackowski KM, van Zijl PC, Calabresi PA, Mori S. Quantitative characterization of the corticospinal tract at 3T. AJNR Am J Neuroradiol 2006;27:2168-2178.

5. Nath A, Venkataramana A, Reich DS, Cortese I, Major EO. Progression of progressive multifocal leukoencephalopathy despite treatment with beta-interferon. Neurology 2006;66:149-150.

6. Reich DS. Case 10: It's "The Vision Thing". MedGenMed 2005;7:58.

7. Aronov, D; Reich DS; Mechler F; Victor JD (2003). Neural coding of spatial phase in V1 of the macaque monkey. J Neurophysiol 89(6): 3304-3327.

   • See the abstract

8. Mechler, F; Reich DS; Victor JD (2002). Detection and discrimination of relative spatial phase by V1 neurons. J Neurosci 22(14): 6129-6157.

   • See the abstract

9. Reich, DS; Mechler F; Victor JD (2001). Independent and redundant information in nearby cortical neurons. Science 294(5551): 2566-2568.

   • See the abstract (from Science Online)

   • See the full text (from Science Online; may require registration)

   • Download the manuscript

   • There is an accompanying Perspectives article in the same issue written by Barry Richmond. Science 2001 294(5551): 2493-2494. May require a personal or institutional subscription. Summary. Full text.

10. Reich, DS; Mechler F; Victor JD (2001). Temporal coding of contrast in primary visual cortex: when, what, and why. J Neurophysiol 85(3): 1039-1050.

    • Download the manuscript

11. Reich, DS; Mechler F; Victor JD (2001). Formal and attribute-specific information in primary visual cortex. J Neurophysiol 85(1): 305-318.

    • Download the manuscript

12. Reich, DS; Mechler F; Purpura KP; Victor JD (2000). Interspike intervals, receptive fields, and information encoding in primary visual cortex. J Neurosci 20(5): 1964-74.

• See a summary

• Download the manuscript

13. Reich DS; Victor JD; Knight BW (1998). The power ratio and the interval map: spiking models and extracellular recordings. J Neurosci 18(23): 10090-104.

• See a summary

• Download the manuscript

14. Reich DS (1997). Review of Spikes: Exploring the Neural Code (by F Rieke, D Warland, RR de Ruyter van Steveninck, W Bialek). Network 8:353-354.

15. Reich DS; Victor JD; Knight BW; Ozaki T; Kaplan E (1997). Precise neuronal spike times coexist with large response variability in vivo. J Neurophysiol 77:2836-2841.

• See a summary

• Download the manuscript

    Abstracts

1. Reich DS, Zackowski KM, Gordon-Lipkin EM, Smith SA, Mori S, Calabresi PA. Relationship of corticospinal tract abnormalities and ankle weakness in multiple sclerosis. American Society of Neuroradiology 2007

2. Reich DS, Zackowski KM, Gordon-Lipkin EM, Smith SA, Chodkowski BA, Gutter GR, Calabresi PA. Corticospinal tract abnormalities associated with weakness in multiple sclerosis. Americas Committee for Research and Treatment in Multiple Sclerosis 2007. One of 6 abstracts chosen for a platform presentation.

3. Zackowski KM, Smith SA, Reich DS, Gordon-Lipkin EM, Bastian AJ, Calabresi PA. Sensorimotor impairments are associated with MRI-defined tract-specific spinal cord disease in multiple sclerosis. Americas Committee for Research and Treatment in Multiple Sclerosis 2007

4. Zackowski KM, Smith SA, Gordon-Lipkin EM, Reich DS, Bastian AJ, Calabresi PA. Relating tract specific spinal cord pathology and sensorimotor impairments in multiple sclerosis. Neural Control of Movement 2007

5. Prucka WR, Coffey CS, Reich DS, Cutter GR. Statistical modeling of clinical outcomes using diffusion tensor image data. Joint Statistical Meetings 2007

6. Gordon-Lipkin EM, Smith SA, Zackowski KM, Pulicken M, Farrell JAD, Reich DS, Calabresi PA. Column-specific cervical spinal cord magnetization transfer abnormality correlates with disability in multiple sclerosis. American Academy of Neurology 2007

7. Gordon-Lipkin EM, Chodkowski BA, Smith SA, Reich DS, Pulicken M, Cettomai D, Balcer LJ, Calabresi PA. Retinal nerve fiber layer thickness correlates with whole brain atrophy in multiple sclerosis. American Academy of Neurology 2007

8. Gordon-Lipkin EM, Chodkowski BA, Smith SA, Reich DS, Pulicken M, Balcer LJ, Gutter GR, Calabresi PA. Retinal nerve fiber layer thickness correlates with brain atrophy in multiple sclerosis. Americas Committee for Research and Treatment in Multiple Sclerosis 2007. One of 6 abstracts chosen for a platform presentation.

9. Reich DS, Zackowski KM, Smith SA, Gordon-Lipkin EM, Mori S, van Zijl PCM, Calabresi PA. Abnormalities in quantitative MR imaging derived corticospinal tract profiles are associated with weakness in multiple sclerosis. Radiological Society of North America 2006

10. Reich DS, Zackowski KM, Gordon-Lipkin EM, Smith SA, Mori S, van Zijl PCM, Calabresi PA. Abnormalities in MRI-derived corticospinal tract profiles are associated with weakness in MS. American Neurological Association 2006

11. Farrell JAD, Smith SA, Gordon-Lipkin EM, Reich DS, Calabresi PA, van Zijl PCM. q-space diffusion weighted MRI of the human spinal cord in vivo: application to multiple sclerosis. International Society for Magnetic Resonance in Medicine 2007

12. Zackowski KM, Reich DS, Smith SA, Mori S, Bastian A, Calabresi PA. Relating sensorimotor function and tract specific MRI in multiple sclerosis. Whitaker Foundation 2006

13. Venkataramana A, Pardo C, McArthur J, Kerr DA, Irani DN, Griffin JW, Burger P, Reich DS, Calabresi PA, Nath A. Immune reconstitution inflammatory syndrome in the CNS of HIV infected patients. 7th International Symposium on NeuroVirology 2006

14. Smith SA, Reich DS, Jones CK, van Zijl PCM, Calabresi PA. Evaluation of the cervical spinal cord in MS with high resolution magnetization transfer MRI at 3T. American Academy of Neurology 2006

15. DeBoy CA, Zhang J, Dike S, Shats I, McMahon M, Jones M, Reich DS, Mori S, Miller RH, Kerr DA, Calabresi PA. Histopathological-MRI correlates using focal myelitis and focal demyelinating rat models. FASEB 2006

16. Smith SA, Jones CK, Reich DS, Calabresi PA, van Zijl PCM. Pulsed magnetization transfer imaging SENSE imaging at 3T. International Society of Magnetic Resonance in Medicine 2005

17. Reich DS, Wakana S, Smith SA, Jones CK, Calabresi PA, Mori S. Differences between the right and left corticospinal tracts in normal adults, revealed by quantitative MRI. American Society of Neuroradiology 2005

18. Reich DS, Smith SA, Jones CK, Dubey P, Zackowski KM, van Zijl PCM, Mori S, Calabresi PA. Abnormalities in white matter fiber tracts in MS revealed by diffusion tensor imaging: Effects at and distant from demyelinating lesions. American Academy of Neurology 2005

19. Dubey P, Reich DS, Smith SA, Jones CK, Zackowski KM, van Zijl PCM, Mori S, Calabresi PA. Multiparamteric MR assessment of lesion heterogeneity in multiple sclerosis. American Neurological Association 2005:#299.

20. Zackowski KM, Reich DS, Smith SA, Mori S, Bastian AJ, Calabresi PA. Relating tract-specific magnetization transfer and diffusion tensor imaging to sensorimotor impairments in multiple sclerosis. Society for Neuroscience 2005:#101.106.

21. Reich DS, Wakana S, Smith SA, Calabresi PA, Mori S. Differences between the right and left corticospinal tracts in normal adults, revealed by diffusion tensor imaging. Regional Conference on Advances in Clinical Auditory Neuroscience: Brain Mapping 2004

22. Victor JD, Mechler F, Reich DS, Aronov D. Metric-space analysis of multineuronal responses: Algorithmic improvements allow for extension to multiple neurons. Soc Neurosci Abstr 2003

23. Aronov D, Reich DS, Mechler F, Victor JD. Multidimensional representation of spatial phase in V1. Association for Research in Vision and Ophthalmology 2001:#2184.

24. Victor JD, Mechler F, Reich DS. Rapidly-converging binless approaches to the calculation of information in spike trains. Soc Neurosci Abstr 2001;27:#821.814.

25. Reich DS; Mechler F; Victor JD (2000). Indpendent and redundant information in V1: Different stimulus types. Neural Information and Coding 2001.

26. Reich DS; Mechler F; Victor JD (2000). Neighboring V1 neurons convey mostly independent messages. Soc Neurosci Abstr 26:2090 (#779.10).

27. Victor JD; Reich DS; Mechler F; Aronov D (2000). Multi-neuronal signaling of spatial phase in V1. Soc Neurosci Abstr 26:2090 (#779.11).

28. Mechler F; Reich DS; Victor JD (2000). How good is spatial phase discrimination in V1? Soc Neurosci Abstr 26:2090 (#779.12).

29. Kalik SF, Schiff ND, Reich DS, Purpura KP. Saccade generation during free viewing in a pattern recognition paradigm. Soc Neurosci Abstr 1999;25:147.141.

30. Reich DS; Mechler F; Victor JD (2000). Information rates in the responses of V1 neurons to temporally rich stimuli. Invest Ophthalmol Vis Sci (Suppl) 41(4):53 (#275).

    • View the poster

31. Mechler F; Reich DS; Victor JD (1999). In V1 complex cells, phase-sensitive receptive field nonlinearities signal a variety of spatial features and violate a pure energy-operator model. Soc Neurosci Abstr 25:1932 (#767.5).

32. Reich DS; Mechler F; Purpura KP; Victor JD (1998). Multiple spatiotemporal messages are conveyed by the dynamic structure of V1 responses. In: Beyond Neurons and Synchrony: The Sixth Annual Dynamical Neuroscience Satellite Symposium, p 67. Los Angeles, CA.

    • View the poster

33. Reich DS; Mechler F; Purpura KP; Knight BW; Victor JD (1998). Multiple timescales are involved in coding of contrast in V1. Soc Neurosci Abstr 24:1257 (#497.1).

    • View the talk

34. Victor JD; Mechler F; Reich DS; Purpura KP (1998). Spatiotemporal origin of bursts and "reliable" spikes generated by neurons in V1. Soc Neurosci Abstr 24:1258 (#497.5).

35. Mechler F; Reich DS; Victor JD (1998). Receptive field nonlinearities in macaque primary visual cortex (V1) are not selectively activated by edges. Soc Neurosci Abstr 24:1979 (#789.3).

36. Reich DS; Knight BW; Victor JD (1998). Simple spiking models and extracellular data: rejecting the Poisson hypothesis, its family, and its friends. FASEB: Retinal Neurobiology and Visual Perception.

    • View the talk

37. Reich DS; Victor JD; Knight BW (1997). A stochastic model of retinal ganglion cell spike generation and the serial correlations between interspike intervals. Soc Neurosci Abstr 23:1819 (#708.2).

    • View the poster

38. Victor J; Mechler F; Schiff N; Reich DS; Purpura K (1997). Representation of spatial phase in the temporal pattern of responses of neurons in V1. Soc Neurosci Abstr 23:568 (#227.5).

    • View related paper

39. Reich DS; Victor JD; Ozaki T; Kaplan E (1996). Precise neuronal firing coexists with large response variability in vivo. Invest Ophthalmol Vis Sci (Suppl) 37(3):688 (#3145).

40. Reich DS; Sanchez-Vives M; Mukherjee P; Kaplan E (1994). Response variability of retinal ganglion cells is independent of the synaptic pathway activated and of retinal illumination. Invest Ophthalmol Vis Sci (Suppl) 35(4):2124 #4032).

41. Mukherjee P; Sanchez-Vives M; Reich DS; Kaplan E (1994). A comparison of the response variability of neurons in the cat LGN with that of their retinal input. Invest Ophthalmol Vis Sci (Suppl) 35(4):1975 (#3340).

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